The Utility of a Medical Cyclotron for Neutron Activation in Research, Teaching and Service.
Over the past 30 years, Canada has witnessed a significant reduction in the number of its operational research nuclear reactors, dwindling from 10 to 3 due to the decommissioning or permanent shutdown of such facilities. This decline has led to a loss of neutron activation analysis (NAA) and radionuclide production capabilities, as well as diminished […]
The Value of Offering an Introductory Radiopharmacy Course at Canadian Universities
The use of radionuclides in nuclear imaging, as well as radiotherapy of cancer and other diseases, is a rapidly growing area in the medical field. Therefore, it is beneficial to offer a course that covers the fundamentals of radiopharmaceutical sciences which includes training and education on the safe-handling and application of radioactive materials. The Fundamentals […]
Safely developing an 18F-Labeling Maltose Dendrimer Radiotracer for Positron Emission Tomography (PET) Imaging of Heparanase
Background: Heparanase, the only mammalian enzyme capable of degrading heparan sulfate (HS), plays a crucial role in various cellular processes including angiogenesis, inflammation, and cancer cell metastasis. Its overexpression in cancer cells makes it an attractive target for anti-cancer therapies. However, the development of heparanase-targeting radiotracers for positron emission tomography (PET) diagnostic imaging or for […]